15 Ethereum Startups in San Francisco: Leading the Charge in Blockchain Innovation

3 mins read

San Francisco is a hotbed for innovation and technology, and it’s no surprise that the city has become a hub for Ethereum startups. With the rise of decentralized finance (DeFi) and blockchain applications, entrepreneurs in San Francisco are leveraging Ethereum’s smart contract capabilities to create exciting products and services. In this article, we’ll showcase 15 Ethereum startups that are making waves in San Francisco.

Origin Protocol: Building Decentralized Marketplaces

Origin Protocol is a blockchain platform that enables the creation of decentralized marketplaces. The platform provides a toolkit for developers to build decentralized applications (dApps) that facilitate peer-to-peer transactions without intermediaries. With Origin, buyers and sellers can interact directly, reducing transaction fees and improving transparency. The project has raised $48 million in funding and has partnered with companies such as Brave, Google, and Shopify.

Kraken: A Leading Crypto Exchange

Kraken is a popular cryptocurrency exchange that offers spot and futures trading for Bitcoin, Ethereum, and over 40 other digital assets. Founded in 2011, the exchange has become one of the largest in the world, serving over 6 million clients. Kraken is known for its robust security measures and commitment to regulatory compliance.

0x: Enabling Peer-to-Peer Trading of Assets

0x is an open protocol that enables peer-to-peer trading of assets on the Ethereum blockchain. The protocol allows developers to build decentralized exchanges (DEXs) that offer non-custodial trading of digital assets. By eliminating the need for centralized exchanges, 0x aims to increase transparency and security in the cryptocurrency trading industry.

Compound: An Open-Source Interest Rate Protocol

Compound is an open-source interest rate protocol that allows users to earn interest or borrow assets on the Ethereum blockchain. The protocol enables a new class of financial applications that are permissionless and transparent. Compound has over $11 billion in assets supplied and has received investment from top venture capital firms such as Andreessen Horowitz and Polychain Capital.

Zerion: An All-in-One DeFi Interface

Zerion is an all-in-one interface that allows users to acquire, track, and manage decentralized finance (DeFi) assets. The platform provides a simple and intuitive interface for both technical and non-technical users. With Zerion, users can view their DeFi portfolio, trade assets, and access lending and borrowing protocols.

The Graph: Offering Indexing and Query for Web3

The Graph is a decentralized indexing and query protocol for Web3 applications. The protocol allows developers to build subgraphs, which are open APIs that can be used to access blockchain data. With The Graph, developers can create powerful dApps that are interoperable with other blockchain networks.

Blocknative: Real-Time Blockchain Transaction Management

Blocknative provides real-time blockchain transaction management and monitoring solutions for public blockchain networks. The platform enables developers to build more reliable dApps that can handle complex transactions. Blocknative has partnered with major blockchain networks such as Ethereum, Binance Smart Chain, and Polygon.

Archblock: Transparent Asset Management Platform

Archblock is building the world’s most transparent and efficient asset management platform. The platform leverages blockchain technology to enable investors to easily invest in digital assets, such as cryptocurrencies, real estate, and art. Archblock has raised over $3 million in funding and is backed by top investors such as Pantera Capital.

Slingshot Finance: Next-Generation Decentralized Trading Platform

Slingshot Finance is a fintech company that offers a next-generation decentralized trading platform. The platform enables users to trade cryptocurrencies, derivatives, and other financial instruments without intermediaries. Slingshot Finance is known for its high-performance trading engine and low fees.

AIKON: Simplifying Blockchain Technology

AIKON makes blockchain technology simple with its cross-chain identity and wallet solutions, ORE ID, and ORE Vault. The platform enables businesses to easily integrate blockchain technology into their existing infrastructure, reducing costs and increasing efficiency. AIKON’s solutions have been used by major companies such as IBM and Deloitte.

Prysm: Community Ownership Platform

Prysm is a community ownership platform that enables users to turn missions into collective movements. The platform allows users to create and manage decentralized autonomous organizations (DAOs), which are self-governing entities that use smart contracts to automate decision-making. Prysm has raised $2.2 million in funding and has partnered with organizations such as MakerDAO and Aave.

Sommelier: Coprocessor for Ethereum

Sommelier is a coprocessor for Ethereum that enables users to move their DeFi assets into higher yields faster and cheaper. The platform leverages advanced algorithms to optimize asset allocation across different DeFi protocols, maximizing returns for users. Sommelier has raised $1.5 million in funding and is backed by major investors such as Pantera Capital and Alameda Research.

Linen App: Signature Wallet for DeFi and Web3

Linen App is a signature wallet for DeFi and Web3 that allows users to securely manage their digital assets. The platform provides a simple and intuitive interface for managing DeFi assets, such as cryptocurrencies and non-fungible tokens (NFTs). Linen App is known for its strong security features and user-friendly design.

Beenest: Home Sharing Platform on Ethereum

Beenest is a home sharing platform on Ethereum that allows hosts to list their homes and for guests to find accommodations. The platform uses smart contracts to automate the booking process, reducing the need for intermediaries. Beenest has raised $15 million in funding and has partnered with companies such as Airbnb and Uber.

Authereum: Onboarding Platform for Decentralized Apps

Authereum is a platform for onboarding users to decentralized apps on the Ethereum network. The platform uses smart contracts to create a seamless and secure onboarding experience for users, reducing the friction associated with using decentralized apps. Authereum has received investment from top venture capital firms such as Coinbase Ventures and Boost VC.


San Francisco is home to some of the most innovative Ethereum startups in the world. From decentralized marketplaces to community ownership platforms, these startups are leveraging Ethereum’s smart contract capabilities to create exciting new products and services. As the Ethereum ecosystem continues to grow, we can expect to see even more exciting startups emerge from San Francisco and beyond.

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