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101 Top Cryptocurrency Startups in San Francisco (Crypto Innovation)

This article showcases our top picks for the best San Francisco based Cryptocurrency companies. These startups and companies are taking a variety of approaches to innovating the Cryptocurrency industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top San Francisco Cryptocurrency Startups

Data sourced from Crunchbase and SemRush.

Solana

Solana

Crunchbase Website Twitter Facebook Linkedin

Solana is a crypto startup that builds and develops crypto apps for decentralized apps and marketplaces.

Coinbase Ventures

Coinbase Ventures

Crunchbase Website Twitter Facebook Linkedin

Coinbase Ventures is an investment arm of Coinbase that aims to invest in early-stage cryptocurrency and blockchain startups.

Coinbase Ventures

Ripple

Crunchbase Website Twitter Facebook Linkedin

Ripple provides one frictionless experience to send money globally using the power of blockchain.

Coinbase Ventures

Blockchain Capital

Crunchbase Website Twitter Facebook Linkedin

Blockchain Capital is a venture capital firm investing in Blockchain-enabled technology companies.

Coinbase Ventures

CoinList

Crunchbase Website Twitter Facebook Linkedin

CoinList is a platform that helps blue-chip crypto projects connect with new token holders.

Coinbase Ventures

Securitize

Crunchbase Website Twitter Facebook Linkedin

Securitize enables digital securities, which are easier to own, simpler to manage, and faster to trade.

Coinbase Ventures

TRM Labs

Crunchbase Website Twitter Facebook Linkedin

TRM Labs monitors digital asset transactions to protect financial institutions from risks like fraud and money laundering.

Coinbase Ventures

Helium

Crunchbase Website Twitter Facebook Linkedin

Helium is an Internet-of-Things developer platform for building the network and transferring IoT device data.

Coinbase Ventures

The Sandbox

Crunchbase Website Twitter Facebook Linkedin

The Sandbox develops a decentralized gaming platform that leverages non-fungible tokens and blockchain technology.

Coinbase Ventures

Mudrex

Crunchbase Website Twitter Facebook Linkedin

Mudrex is a cryptocurrency company that specializes in autopilot smart crypto investment.

Coinbase Ventures

Wyre

Crunchbase Website Twitter Facebook Linkedin

Wyre develops a wide variety of payment APIs that offer a fast and cost-effective way of transferring money.

Coinbase Ventures

Bitwise

Crunchbase Website Twitter Facebook Linkedin

Bitwise is a crypto index fund manager for individuals, investment managers, and institutions navigating cryptocurrency.

Coinbase Ventures

Iron Fish

Crunchbase Website Twitter Facebook Linkedin

Iron Fish is a novel cryptocurrency focused on privacy and accessibility.

Coinbase Ventures

MobileCoin

Crunchbase Website Twitter Facebook Linkedin

MobileCoin is a cryptocurrency platform that provides anti-fraud services and payment systems for merchants.

Coinbase Ventures

dYdX

Crunchbase Website Twitter Facebook Linkedin

dYdX is a leading decentralized exchange offering Perpetual, Margin, & Spot trading, as well as borrow / lend pools on Ethereum.

Coinbase Ventures

Chia Network

Crunchbase Website Twitter Facebook Linkedin

Chia Network is building a blockchain platform based on Proofs of Space and Time.

Coinbase Ventures

Eco

Crunchbase Website Twitter Facebook Linkedin

Eco isn’t a bank. It’s something better — a digital wallet that rewards you every time you save, spend or send money.

Coinbase Ventures

Compound

Crunchbase Website Twitter Facebook Linkedin

Compound is an open-source interest rate protocol that unlocks new financial applications.

Coinbase Ventures

Paradigm

Crunchbase Website Twitter Facebook Linkedin

Paradigm primarily invests in crypto-assets and businesses from the earliest stages of idea formation through to maturity.

Coinbase Ventures

Anchorage Digital

Crunchbase Website Twitter Facebook Linkedin

Anchorage Digital is a digital asset platform offering custody, trading, and financing services, as well as staking and governance.

Coinbase Ventures

Portal

Crunchbase Website Twitter Facebook Linkedin

Portal is a financial services company that trades crypto without putting coins at risk.

Coinbase Ventures

CoinTracker

Crunchbase Website Twitter Facebook Linkedin

CoinTracker is a portfolio and tax manager for cryptocurrency.

Coinbase Ventures

0x

Crunchbase Website Twitter Facebook Linkedin

0x is an open protocol that enables peer-to-peer trading of assets.

Coinbase Ventures

Aleo

Crunchbase Website Twitter Facebook Linkedin

Aleo develops a platform that enables absolute privacy on Blockchains.

Coinbase Ventures

NuCypher

Crunchbase Website Twitter Facebook Linkedin

NuCypher is a cryptography company that builds privacy-preserving infrastructure and protocols.

Coinbase Ventures

Slingshot Finance

Crunchbase Website Twitter Facebook Linkedin

Next-gen decentralized trading platform

Coinbase Ventures

Fei Protocol

Crunchbase Website Twitter Facebook Linkedin

Fei Protocol is a direct incentive stable coin which is undercollateralized and fully decentralized.

Coinbase Ventures

Zerion

Crunchbase Website Twitter Facebook Linkedin

Zerion is an all-in-one interface that allows technical and non-technical users to acquire, track and manage DeFi assets.

Coinbase Ventures

Layer1

Crunchbase Website Twitter Facebook Linkedin

Layer1 builds turnkey Bitcoin mining data centers that boost the profitability of energy assets.

Coinbase Ventures

Set Labs

Crunchbase Website Twitter Facebook Linkedin

Set Labs is a crypto-financial platform that allows users to create baskets of cryptocurrency, NFTs, and on-chain securities.

Coinbase Ventures

Connext

Crunchbase Website Twitter Facebook Linkedin

Connext is a crosschain liquidity network that enables fast, fully-noncustodial transfers between EVM-compatible chains and L2 systems.

Coinbase Ventures

O(1) Labs

Crunchbase Website Twitter Facebook Linkedin

O(1) Labs is a software development company working on Mina Protocol, a tiny, portable blockchain.

Coinbase Ventures

BOSONIC

Crunchbase Website Twitter Facebook Linkedin

BOSONIC is a Fintech platform that eliminates counterparty credit and settlement risk in digital assets trading.

Coinbase Ventures

Stellar Development Foundation

Crunchbase Website Twitter Facebook Linkedin

Stellar Development Foundation supports the development and growth of Stellar, a blockchain network that connects financial infrastructure.

Coinbase Ventures

SKALE Labs

Crunchbase Website Twitter Facebook Linkedin

SKALE Labs is a blockchain scalability platform that provides high speed consensus and empowers dApps to run smart contracts.

Coinbase Ventures

River Financial

Crunchbase Website Twitter Facebook Linkedin

River Financial is a Bitcoin financial institution allowing long-term investors to buy, sell, and manage Bitcoin.

Coinbase Ventures

FanTrade

Crunchbase Website Twitter Facebook Linkedin

FanTrade is a mobile app where users earn money by playing real-time daily contests based on fantasy crypto and stocks.

Coinbase Ventures

Harbor

Crunchbase Website Twitter Facebook Linkedin

Harbor is helping to power the next big wave in capital markets – tokenized securities – by automating regulatory compliance.

Coinbase Ventures

Kava Labs

Crunchbase Website Twitter Facebook Linkedin

Kava Labs is a developer of Kava, is the most trusted DeFi platform by financial institutions

Coinbase Ventures

TrueFi

Crunchbase Website Twitter Facebook Linkedin

TrueFi is the ultimate DeFi uncollateralized lending protocol

Coinbase Ventures

Apto Payments

Crunchbase Website Twitter Facebook Linkedin

Apto Payments is a card issuance platform that helps companies issue new kinds of cards in new ways.

Coinbase Ventures

Saddle Finance

Crunchbase Website Twitter Facebook Linkedin

Saddle Finance is an automated market maker (AMM) optimized for pegged value crypto assets.

Coinbase Ventures

Risk Harbor

Crunchbase Website Twitter Facebook Linkedin

The only objective, transparent, and fully automated risk management marketplace for decentralized finance (DeFi).

Coinbase Ventures

Bitwave

Crunchbase Website Twitter Facebook Linkedin

Bitwave is a digital asset management platform that supplies back-office software solutions to enterprises that accept cryptocurrencies

Coinbase Ventures

Hawku

Crunchbase Website Twitter Facebook Linkedin

http://hawku.com is building the marketplace for utility and gaming NFTs. Currently Hawku provides listings, sales and data for Zed horses.

Coinbase Ventures

Commonwealth Labs

Crunchbase Website Twitter Facebook Linkedin

Commonwealth Labs is a governance startup offering a new twist on token airdrops.

Coinbase Ventures

XMargin

Crunchbase Website Twitter Facebook Linkedin

XMargin utilizes zero-knowledge proof technology to provide cross-margin, credit and settlement services for the financial markets.

Coinbase Ventures

Thesis

Crunchbase Website Twitter Facebook Linkedin

Thesis is a cryptocurrency venture studio funding and building decentralized products and protocols that enable personal empowerment.

Coinbase Ventures

Rare Bits

Crunchbase Website Twitter Facebook Linkedin

Rare Bits is a zero-fee peer-to-peer marketplace to buy, sell, and discover crypto goods.

Coinbase Ventures

Opyn

Crunchbase Website Twitter Facebook Linkedin

Opyn allows users to earn a premium or take views on assets by trading options on ETH and ERC20s.

Coinbase Ventures

fxdx exchange

Crunchbase Website Twitter Facebook Linkedin

Derivatives DEX with lightning-fast transaction speed and minimal transactions costs with institutional-grade centralized UI/UX experience

Coinbase Ventures

Omniex

Crunchbase Website Twitter Facebook Linkedin

Omniex develops software infrastructure that integrates front, middle, and back-office services to simplify access and remove fragmentation.

Coinbase Ventures

Prysm

Crunchbase Website Twitter Facebook Linkedin

a social investing economy enabled by web3

Coinbase Ventures

Reflexer Labs

Crunchbase Website Twitter Facebook Linkedin

Reflexer Labs is a new decentralized finance project aimed at softening volatility.

Coinbase Ventures

Async Art

Crunchbase Website Twitter Facebook Linkedin

Collect and Experience Rare Programmable Art.

Coinbase Ventures

Provenance Blockchain

Crunchbase Website Twitter Facebook Linkedin

Provenance Blockchain combines the distributed, trustless, and immutable characteristics of blockchain.

Coinbase Ventures

Agoric

Crunchbase Website Twitter Facebook Linkedin

Agoric provides a framework for programming smart contracts securely and with ease, beyond anything available today.

Coinbase Ventures

MetaMask

Crunchbase Website Twitter Facebook Linkedin

MetaMask is a crypto wallet that allows users to manage their digital assets through a browser extension or mobile app.

Coinbase Ventures

Multis

Crunchbase Website Twitter Facebook Linkedin

Multis provides financial services for companies holding euros, dollars, and cryptocurrencies.

Coinbase Ventures

Linen App

Crunchbase Website Twitter Facebook Linkedin

New experience that allows our members to earn high yield on their cash.

Coinbase Ventures

Puma Browser

Crunchbase Website Twitter Facebook Linkedin

Puma is a mobile browser and wallet for the Web3 ecosystem. Private by design.

Coinbase Ventures

BarnBridge

Crunchbase Website Twitter Facebook Linkedin

Tokenized risk protocol

Coinbase Ventures

Staax

Crunchbase Website Twitter Facebook Linkedin

Staax makes building wealth through investing in shares of stock as easy as receiving payment from your friends.

Coinbase Ventures

AnchorUSD

Crunchbase Website Twitter Facebook Linkedin

AnchorUSD offers stable currency anchored 1-for-1 to the US dollar (USDX).

Coinbase Ventures

Jointer

Crunchbase Website Twitter Facebook Linkedin

World’s first COMMERCIAL REAL ESTATE BACKED DeFi

Coinbase Ventures

Deep Discovery

Crunchbase Website Twitter Facebook Linkedin

Artificial intelligence for fighting global corruption

Coinbase Ventures

Idex.io

Crunchbase Website Twitter Facebook Linkedin

Idex.io is a decentralized cryptocurrency exchange.

Coinbase Ventures

Snowball Money

Crunchbase Website Twitter Facebook Linkedin

Snowball Money operates as a crypto investment automation platform that provides access to professionally curated portfolios.

Coinbase Ventures

Round Finance Inc.

Crunchbase Website Twitter Facebook Linkedin

Building an aggregator of digital assets and experiences

Coinbase Ventures

Swing Finance

Crunchbase Website Twitter Facebook Linkedin

Swing is a decentralized cross-chain liquidity protocol on top layer 1 & 2 blockchains.

Coinbase Ventures

CASPIAN

Crunchbase Website Twitter Facebook Linkedin

CASPIAN is a full stack crypto asset management solution.

Coinbase Ventures

SIREN

Crunchbase Website Twitter Facebook Linkedin

SIREN is a distributed protocol creating a decentralized blockchain exchange for options trading on Ethereum.

Coinbase Ventures

TokenInsight

Crunchbase Website Twitter Facebook Linkedin

TokenInsight is dedicated towards providing accurate data and ratings for cryptocurrency companies through transparency.

Coinbase Ventures

Phantom

Crunchbase Website Twitter Facebook Linkedin

Phantom is a digital wallet reimagined for DeFi and NFTs.

Coinbase Ventures

Purse

Crunchbase Website Twitter Facebook Linkedin

Purse provides real incentive to use Bitcoin to the largest selection at the lowest price points.

Coinbase Ventures

Cryptiswap

Crunchbase Website Twitter Facebook Linkedin

CryptiSwap© is a Non-Custodial CryptoCurrency swap platform | no registration | no holds

Coinbase Ventures

SureRemit

Crunchbase Website Twitter Facebook Linkedin

SureRemit is an ecosystem for global non-cash remittances.

Coinbase Ventures

BUTTON Wallet

Crunchbase Website Twitter Facebook Linkedin

BUTTON Wallet is multi crypto currency wallet with exchange in Telegram

Coinbase Ventures

gumi Cryptos Capital (gCC)

Crunchbase Website Twitter Facebook Linkedin

gumi Cryptos Capital is a blockchain and cryptographic asset venture fund

Coinbase Ventures

Bitski

Crunchbase Website Twitter Facebook Linkedin

Bitski allows creators, brands, and platforms to create, sell, and purchase NFTs.

Coinbase Ventures

TrustToken

Crunchbase Website Twitter Facebook Linkedin

TrustToken is a platform to create asset-backed tokens that can be used for buying and selling around the world.

Coinbase Ventures

Token Daily

Crunchbase Website Twitter Facebook Linkedin

Token Daily operates an online news publishing platform intended to provide news on the cryptocurrency and blockchain market.

Coinbase Ventures

Bitnet Technologies

Crunchbase Website Twitter Facebook Linkedin

Bitnet Technologies is a digital commerce platform that helps enterprise scale merchants to accept bitcoin payments.

Coinbase Ventures

DCEX

Crunchbase Website Twitter Facebook Linkedin

DCEX is a US based digital currency exchange with OTC desk, digital dollar DCEX$ and a Digital currency news site

Coinbase Ventures

Filta

Crunchbase Website Twitter Facebook Linkedin

Filta is an NFT marketplace that sells limited-edition face filter NFTs by favorite independent artists.

Coinbase Ventures

Yours

Crunchbase Website Twitter Facebook Linkedin

Yours is a blockchain-based social network where users can earn bitcoin.

Coinbase Ventures

Beanstalk Network

Crunchbase Website Twitter Facebook Linkedin

Beanstalk Network is a research and development company for privacy preserving financial transactions.

Coinbase Ventures

Stronghold

Crunchbase Website Twitter Facebook Linkedin

Stronghold creates virtual payment networks that give developers access legacy and next-generation payment networks through a simple API.

Coinbase Ventures

Coinfeeds

Crunchbase Website Twitter Facebook Linkedin

Coinfeeds is an API that tracks and aggregates news and social sentiment for crypto enthusiasts.

Coinbase Ventures

Speakezee

Crunchbase Website Twitter Facebook Linkedin

Web3 native podcasting platform

Coinbase Ventures

Standard Crypto

Crunchbase Website Twitter Facebook Linkedin

Standard Crypto is an investment firm.

Coinbase Ventures

Volt Capital

Crunchbase Website Twitter Facebook Linkedin

Volt Capital is a research and community driven crypto fund.

Coinbase Ventures

2Cents

Crunchbase Website Twitter Facebook Linkedin

2Cents is an ethereum protocol that turns users into network owners for internet communities.

Coinbase Ventures

Picks & Shovels

Crunchbase Website Twitter Facebook Linkedin

The Picks & Shovels Co. crafting tools for investors and traders of digital currencies and crypto assets.

Coinbase Ventures

ChangeTip

Crunchbase Website Twitter Facebook Linkedin

ChangeTip facilitates global micropayments across every social media or digital platform.

Coinbase Ventures

Ribbon Finance

Crunchbase Website Twitter Facebook Linkedin

Ribbon Finance creates structured products that deliver sustainable yield using financial engineering for DeFi.

Coinbase Ventures

Apifiny

Crunchbase Website Twitter Facebook Linkedin

A global digital asset trading network unifying fragmented markets, providing superior liquidity and trade execution for professionals.

Coinbase Ventures

Common Interest

Crunchbase Website Twitter Facebook Linkedin

Blockchain, Decentralized Organization, Crypto, Cryptocurrencies

Coinbase Ventures

Binance.US

Crunchbase Website Twitter Facebook Linkedin

Binance is a cryptocurrency exchange that provides a platform for trading various cryptocurrencies.

Coinbase Ventures

Hexel

Crunchbase Website Twitter Facebook Linkedin

Hexel is a startup that wants to make it easy for anyone to use Ethereum-based tokens to engage their hyperlocal community.

Coinbase Ventures

Satochi

Crunchbase Website Twitter Facebook Linkedin

Fintech, Investing, Cryptocurrency, Consumer

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